Tips:
Based on the clinical responsive outcome, this module requires users to select a certain cancer type and dataset, then users need to select a certain sampling timepoint and tissue type, and finally select a certain cell type they are interested. This procedure guarantees that the cell type user selected are specifically from the same cancer type, dataset, timepoint and tissue type. The result format returned in this module is the same as the Pre VS Post module described above. Firstly, a volcano plot is intuitively presented for users to show the underlying significantly differential expressed genes between R and NR. Secondly, detailed differential gene expression table will also be returned so that users can screen genes they are interested in and check their up or down trend during the treatment of ICB. Thirdly, the GO and KEGG enrichment results of specific up-regulated genes in both R and NR treatment group will also be returned so that users can directly know which signaling pathways or gene signatures are enriched in R or NR group. All clinical information, expression table and figures for visualization can be downloaded.